Repeatability of DTI and tractography biomarkers in healthy kidneys

Motivation: For clinical application uncertainty of DTI and tractography biomarkers is critical to avoid that management decisions are made based on changes that are due to measurement error. Goal(s): Provide a comprehensive reference guide of estimated uncertainties for DTI and tractography renal biomarkers and use the data to screen these biomarkers based measurement precision. Approach: Five healthy-volunteers were scanned 4 times on 3T MRI scanner using a diffusion free-breathing protocol. DTI and tractography parameters were calculated using DIPY. Results: Tractography markers are less precise than DTI, sphericity is the most reliable of all DTI metrics, and histogram metrics kurtosis and skewness are inherently imprecise. Impact: This study presents comprehensive reference values for error ranges in renal DTI that will help to identify real (patho)physiological changes in future clinical results

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/0784
Primary Topic
MRI in cancer diagnosis
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Repeatability of DTI and tractography biomarkers in healthy kidneys

Mark Gilchrist, David Shelley, Maria F. Gomez, Kywe Kywe Soe et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
MRI in cancer diagnosis
article

Repeatability of DTI and tractography biomarkers in healthy kidneys

Mark Gilchrist, David Shelley, Maria F. Gomez, Kywe Kywe Soe, João Periquito, Angela C. Shore, Kanishka Sharma, Kim M. Gooding, Steven Sourbron, Jonathan Fulford, Bashair Alhummiany
article en

Abstract

Motivation: For clinical application uncertainty of DTI and tractography biomarkers is critical to avoid that management decisions are made based on changes that are due to measurement error. Goal(s): Provide a comprehensive reference guide of estimated uncertainties for DTI and tractography renal biomarkers and use the data to screen these biomarkers based measurement precision. Approach: Five healthy-volunteers were scanned 4 times on 3T MRI scanner using a diffusion free-breathing protocol. DTI and tractography parameters were calculated using DIPY. Results: Tractography markers are less precise than DTI, sphericity is the most reliable of all DTI metrics, and histogram metrics kurtosis and skewness are inherently imprecise. Impact: This study presents comprehensive reference values for error ranges in renal DTI that will help to identify real (patho)physiological changes in future clinical results

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Good health and well-being
Openalex Percentile: Top 64%
MRI in cancer diagnosis
DOISourceOpenAlex
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Repeatability of DTI and tractography biomarkers in healthy kidneys — Mark Gilchrist, David Shelley, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2024) | TGRS Research Map | TGRS