Central Vein Sign and Trigeminal Lesions of Multiple Sclerosis Visualized by 7.0T MRI

Motivation: Multiple sclerosis patients are more vulnerable to trigeminal neuralgia, but the mechanism behind this nerve injury is still unclear. Goal(s): We aim to investigate trigeminal nerve involvement in MS and provide insight into pathology. Approach: 120 patients underwent 7.0 T multi-modality MRI scans. T1-MPRAGE, T2-FLAIR, FLAWS-MP2RAGE, and T2*W images were collected. Results: Our study confirmed the high prevalence of trigeminal nerve on 7.0 T MRI and highlighted the presence of a central vein sign in trigeminal nerve lesions. This study contributes to a deeper understanding of the pathophysiology and location-specific nature of trigeminal lesions. Impact: This finding reinforces that trigeminal nerve involvement represents a characteristic of MS lesions, which has the potential for precising diagnosis in the future.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/2955
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

Central Vein Sign and Trigeminal Lesions of Multiple Sclerosis Visualized by 7.0T MRI

Huabing Wang, Emmanuelle L. Waubant, Lei Su, Xinghu Zhang et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Radiomics and Machine Learning in Medical Imaging
article

Central Vein Sign and Trigeminal Lesions of Multiple Sclerosis Visualized by 7.0T MRI

Huabing Wang, Emmanuelle L. Waubant, Lei Su, Xinghu Zhang, Yaou Liu, De‐Cai Tian, Zhe Zhang, Jing Jing, Fu‐Dong Shi, Chenyang Gao, Xinyao Liu, Yuan Li
article en

Abstract

Motivation: Multiple sclerosis patients are more vulnerable to trigeminal neuralgia, but the mechanism behind this nerve injury is still unclear. Goal(s): We aim to investigate trigeminal nerve involvement in MS and provide insight into pathology. Approach: 120 patients underwent 7.0 T multi-modality MRI scans. T1-MPRAGE, T2-FLAIR, FLAWS-MP2RAGE, and T2*W images were collected. Results: Our study confirmed the high prevalence of trigeminal nerve on 7.0 T MRI and highlighted the presence of a central vein sign in trigeminal nerve lesions. This study contributes to a deeper understanding of the pathophysiology and location-specific nature of trigeminal lesions. Impact: This finding reinforces that trigeminal nerve involvement represents a characteristic of MS lesions, which has the potential for precising diagnosis in the future.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 64%
Radiomics and Machine Learning in Medical Imaging
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Central Vein Sign and Trigeminal Lesions of Multiple Sclerosis Visualized by 7.0T MRI — Huabing Wang, Emmanuelle L. Waubant, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2024) | TGRS Research Map | TGRS