Human Resting-State Complexity of BOLD fMRI in Ultra-High-Field MRI at 7T: a primer
Motivation: BOLD-fMRI intrinsic functional connectivity has limited capability to assess the temporal dynamics of complex brain networks. The insufficient signal-to-noise ratio of 3T MRI might prevent the detection of subtle alterations. Goal(s): Detecting resting-state complexity alterations in healthy subsamples using 7T MRI. Approach: Multiscale entropy was computed for ten scales from 0.1 to 1 Hz. A whole-brain ANCOVA was conducted to assess entropy differences of the scales between 30 healthy adults with spider phobia and 45 without. Results: Spider phobia showed decreased entropy in several fear-related brain regions in all scales except 1 Hz. Impact: 7T fMRI detected reduced high-frequency resting-state multiscale entropy related to spider phobia, indicating worse local processing of fear and memory-related brain regions.
Authors
- Niklaus Denier (ORCID: https://orcid.org/0000-0002-3996-9148)
- Werner Strik (ORCID: https://orcid.org/0000-0001-7108-1993)
- Leila M. Soravia (ORCID: https://orcid.org/0000-0002-4924-7771)
- Elisabeth Jehli (ORCID: https://orcid.org/0000-0001-7188-1798)
- Kay Jann (ORCID: https://orcid.org/0000-0003-3574-0538)
- Matthias Grieder (ORCID: https://orcid.org/0000-0002-5124-5302)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/3450
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00