White matter changes across the migraine cycle evaluated with Diffusion Tensor Imaging and the impact of Free Water
Motivation: About 25% of female migraine patients suffer from menstrual-related migraine, which has been poorly studied. Goal(s): To identify white matter alterations across the migraine cycle in patients with episodic menstrual-related migraine without aura. Approach: Diffusion MRI allows to assess alterations in the brain tissue microenvironment. Moreover, including the free-water contribution in the diffusion signal can give information about biological mechanisms, such as inflammation, and more directly expose the tissue alterations by removing free water contamination. Results: Significant differences were found in the diffusion parameters of the white matter tracts of the menstrual-related migraine patients. Impact: We found significant alterations in the diffusion parameters of the white matter tracts of episodic menstrual-related migraine patients across migraine cycle using standard diffusion tensor imaging (DTI) and Free-Water corrected DTI.
Authors
- Gina Caetano (ORCID: https://orcid.org/0000-0001-6878-6079)
- Irene Guadilla (ORCID: https://orcid.org/0000-0002-3932-0840)
- Amparo Ruiz‐Tagle (ORCID: https://orcid.org/0000-0003-4689-9536)
- Antonio Tristán‐Vega (ORCID: https://orcid.org/0000-0002-4614-2501)
- Rita Nunes (ORCID: https://orcid.org/0000-0001-8271-6579)
- Santiago Aja‐Fernández (ORCID: https://orcid.org/0000-0002-5337-5071)
- Raquel Gil‐Gouveia (ORCID: https://orcid.org/0000-0002-4256-4256)
- Patrícia Figueiredo (ORCID: https://orcid.org/0000-0002-0743-0869)
- Álvaro Planchuelo‐Gómez (ORCID: https://orcid.org/0000-0002-2188-4197)
- Inês Esteves (ORCID: https://orcid.org/0000-0002-7082-0026)
- Ana R. Fouto (ORCID: https://orcid.org/0000-0002-0362-9571)
- Pedro Vilela (ORCID: https://orcid.org/0000-0002-2975-8566)
- Nuno André Silva (ORCID: https://orcid.org/0000-0002-1061-1716)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/0123
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00