Enhancing liver reserve function prediction in liver cancer through Gd-EOB-DTPA and DWI: Insights on CD34 and glypican-3 expression levels

Motivation: The quantitative magnetic resonance imaging of Gd-EOB-DTPA has been employed to predict liver reserve function, tolerance, and postoperative recovery in patients with primary liver cancer. Goal(s): To investigate the relationship between quantitative parameters, liver reserve function of primary liver cancer and the expression levels of CD34 and Glypican-3. Approach: Evaluate the correlation between REHBP, ADC, liver function classification, and immune markers CD34 and Glypican-3Results: In comparison to patients with benign liver nodules, patients with primary liver cancer exhibited significantly lower REHBP and ADC values. Impact: The combination DCE-MRI with Gd-EOB-DTPA and DWI has a predictive value for liver reserve function and prognostic molecular marker expression in patients with primary liver cancer. It can also serve as a useful reference index for clinical preoperative planning.