A new approach for reproducible water fraction and T1 mapping across different qMRI acquisition protocols

Motivation: The quantitative MRI community uses various acquisition approaches to extract the same quantitative maps while continuously working to find the agreement between them. Goal(s): Our goal was to examine the agreement between the outcomes of two acquisition approaches, variable flip angle and MP2RAGE. Approach: We produced a postprocessing method that generated qMRI maps from both acquisition approaches and controlled the similarities between the maps. Results: Our new approach produced strong correlations between qMRI maps acquired with different sequences, emphasizing the agreement and consistency between them. Impact: Our approach provides high agreement between different qMRI acquisition strategies, that may allow harmonization between different scanners and MR protocols and enable the usage of multiple datasets for research purposes.