Determining grade and subtype of meningiomas with inversion recovery multiple overlapping-echo detachment imaging

Motivation: T2 mapping with FLAIR eliminates the interference of cerebrospinal fluid, depicting lesion more precise than conventional T2 mapping, but its use for grading and classifying meningiomas is scarce. Goal(s): To investigate the value of a single-shot T2-FLAIR mapping method, inversion recovery multiple overlapping-echo detachment imaging (IR-MOLED), in distinguishing grades and subtypes of meningiomas. Approach: IR-MOLED was applied on meningioma patients (N = 45), and histogram analysis of enhanced tumor regions was performed based on the resultant parametric maps. Results: T2-FLAIR mapping is sensitive in determining the meningiomas grade (AUC = 0.813) and subtype (AUC = 0.971). Impact: IR-MOLED-based quantitative analysis is promising in differentiating high and low grades and subtypes of meningiomas, especially in patients losing body control.