Ultrashort Echo Time (UTE) Spiral-VIBE MRI for Lung Nodule Detection and Radiomics Feature Stability Assessment

Motivation: This study aims to assess the efficacy of UTE-MRI in detecting lung nodules compared to CT and to evaluate the stability of radiomics features, along with the factors influencing them. Goal(s): Through the advancement of UTE scanning technology, we strive to enable MRI to achieve lung nodule detection capability and stability on par with CT. Approach: To facilitate the clinical integration of UTE technology for lung diseases, UTE scanning was conducted on patients presenting with lung nodules. Results: UTE-MRI demonstrates a high detection rate for lung nodules larger than 6 mm, and it exhibits a high level of stability in radiomics features. Impact: Our study shows UTE showcasing a remarkable ability to detect lung nodules larger than 6 mm and maintain consistent radiomics features across repeated scans. UTE holds potential as a radiation-reducing alternative to CT for regularly monitored patients with lung nodules.