Preoperative Left Atrial Strain Predicts Outcome in Patients with Hypertrophic Obstructive Cardiomyopathy after Myectomy

Motivation: The association of preoperative LA strain assessed by cardiac magnetic resonance (CMR)-FT with the late outcome of HOCM patients after myectomy remains unknown. Goal(s): To evaluate the prognostic value of preoperative LA strain in HOCM following myectomy. Approach: In this retrospective, single-center study, 802 adult patients with HOCM after myectomy were included, who underwent preoperative CMR with clinical outcome follow-up. Results: LA reservoir strain ≤ 22.9% was independently associated with postoperative adverse outcomes. Incorporating LA reservoir strain, the performance of the HCM Risk-SCD score improved for SCD prediction (C-statistic: from 0.62 to 0.69; log-likelihood: from -110.31 to -108.27, P=.04). Impact: HOCM patients with reduced preoperative LA reservoir strain tend to have poor postoperative outcomes, so reinforced follow-ups may be required in those patients.