Rapid 3D slab-selective MR elastography using interleaved motion encoding

Motivation: Most current volumetric 3D MRE sequences are restricted to 2D slice acquisitions, but we propose a novel sequence for rapid 3D slab-selective MRE. Goal(s): To demonstrate the feasilbility of a 3D slab-selective MRE sequence with an interleaved motion encoding scheme. Approach: The proposed 3D MRE sequence allows the measurement of different wave offsets and motion encodings for a 3D slab in a single measurement with a constant repetition time, minimising total acquisition time. Results: We show initial results of the proposed technique in a phantom and for a single breathhold 3D liver MRE in a healthy subject. Impact: The proposed method can be applied for effiicient 3D high-resolution MRE. Applications include liver fibrosis and inflammation staging, but the sequence may also be used for brain MRE.