Accelerated and Accurate Myocardial Multi-Parametric Quantitative Mapping using Bloch Equation Simulation-based Fitting

Motivation: Motivated by the time-consuming process of dictionary matching in quantitative cardiac MRI, this study aims to develop a faster and more accurate method for myocardial multi-parametric quantitative mapping. Goal(s): The goal is to overcome the limitations of discretization errors and incomplete inversion pulses, which lead to inaccurate parameter estimation. Approach: The proposed approach utilizes Bloch equation simulation-based fitting, enabling rapid reconstruction of T1, T2, and T1ρ maps simultaneously. Results: Experimental results demonstrate excellent quality of fit and significant acceleration (100x) compared to the traditional method. Impact: This novel method has the potential to revolutionize myocardial quantitative mapping, offering improved efficiency and precision in clinical applications.