Time-Resolved Cardiac function: Myocardium Strain and First-Pass Perfusion Using MR-MOTUS

Motivation: We aim at improving accuracy and reliability in cardiac imaging for coronary artery disease diagnosis and management. We address motion artifacts in first-pass myocardial perfusion MR imaging. Goal(s): To develop and validate motion correction techniques for motion field accuracy and strain quantification in non-ECG triggered myocardial first pass perfusion examinations. Approach: We use a modified MR-MOTUS framework for motion separation and reconstruction in patient data. Results: Our approach demonstrates higher accuracy in respiratory/cardiac motion field estimation with additional strain analysis. Impact: Our findings have the potential to improve patient care by enabling free-breathing and non-ECG triggered examinations of myocardial first-pass perfusion simultaneously with strain analysis. We also open avenues for further research in cardiac imaging and motion correction techniques.