MRI and tumor-infiltrating CD8+ T cell-based nomogram for predicting meningioma recurrence risk stratification

Motivation: To investigate the efficacy of MRI features and CD8+ T cells in predicting risk stratification for meningioma recurrence. Goal(s): To develop a reliable nomogram incorporating MRI features and CD8+ T cells to predict meningioma recurrence. Approach: Conventional MRI features, ADC histogram parameters, and CD8+ T cells were recorded and compared. This model was the first to combine clinical, imaging, and TME data to predict meningioma recurrence. Results: The ADCp1 and CD8+ T cells as predictive variables for meningioma recurrence and patients with low ADCp1 or CD8+ T cell counts had higher recurrence rates than those with high ADCp1 or CD8+ T cell counts. Impact: The findings will improve prognostic accuracy for patients with meningioma and potentially allow for targeted treatment of individuals who have the recurrent form.