Renal perfusion quantification using multi delay Pseudo-continuous Arterial Spin Labeling: Comparison of results at 1.5T and 3T field strengths

Motivation: Pseudo-continuous Arterial Spin Labeling (PCASL) MRI is a promising technique for assessing renal perfusion. Previous studies have been carried out at 1.5T and 3T field strengths, but a comparison of data acquired at both field strengths has never been performed. Goal(s): The aim of this work was to assess the effects of field strength on the measured perfusion signal and to evaluate the reproducibility of renal PCASL at both fieldsApproach: Healthy volunteers underwent repeated scans on both scanners, spaced a week apart. Results: The results showed excellent reproducibility and minimal differences in RBF, ATT and T1 values between visits and field strengths. Impact: The similarity in the study results across both field strengths underscore the potential for expanding PCASL-based renal perfusion assessment, increasing the technique accessibility, and widening diagnostic capabilities.