Analysis of postural effect on cardiac function using multiposture MRI

Motivation: Cardiac function is affected by body posture. However, MRI measurements have been limited to the supine posture. Goal(s): Our goal was to evaluate the effect of body posture on cardiac function using multiposture MRI. Approach: We assessed cardiac function in supine and standing postures in seven healthy males using a 0.4T multiposture MRI. Results: Significant reductions in left ventricular end-diastolic volume, end-systolic volume, and stroke volume were observed in the standing posture, with increased heart rate, while cardiac output and ejection fraction remained consistent across postures. Impact: Multiposture MRI enables the assessment of the postural effect on cardiac function and potentially provides new diagnostic insights into regulatory response to postural change.