Noninvasive Early Detection and Stage of Chronic Lung Diseases with Precision MRI (pMRI)

Motivation: MRI diagnosis of lung has a limitation due to the air in the lungs which prevents the water signals. We use precision MRI to image the small lesions or fibrosis in the lung. Goal(s): Our goal is to quantitatively stage the lung diseases by MRI contrast agents. Approach: Our novel MRI contrast agent is biomarker specific which enables it target to the lung lesions or fibrosis. Results: We are able to image the lung cancer and metastasis as well as lung fibrosis using our developed MRI contrast agent. Impact: The imaging of lung tumor lesion or fibrosis is always hindered by the lung features. Our novol contrast agents enable us to image the lung diseases at early stages.