The Optimal Timepoint for Lesion depiction in Ultrafast DCE MRI: Correlation with lesion size and Invasive Breast Cancer Subtype

Motivation: To know the factors affecting optimal timing of lesion evaluation in ultrafast (UF)- DCE MRI other than BPE. Goal(s): To investigated the optimal timing for lesion depiction on UF-DCE MRI in relation to lesion size and invasive breast cancer subtype. Approach: Optimal timing of lesion evaluation over 400 lesions were assessed by experienced readers. Its association with lesion size and subtype were examined. Results: Optimal timing of breast lesion evaluation on UF-DCE MRI can be earlier for those with larger lesion, and not affected by subtype in case of invasive carcinoma. Impact: UF-DCE MRI normally involves hundreds of images with multiple timing. Predicting optimal timing before scanning may help in efficient reading, efficient post-processing/reconstruction, and protocol improvement. The current results indicate the impact of lesion size, not subtype on optimal timing.