Quantitative Assessment of Perineural Invasion in Cervical Carcinoma using IVIM Combined with mDixon-Quant Multiparameter Imaging

Motivation: Perineural invasion (PNI) is a significant prognostic factor in cervical carcinoma（CC）. The utilization of quantitative parameters derived from IVIM and mDixon-Quant MRI offers a new approach for evaluating PNI in CC. Goal(s): This study aimed to investigate the potential value of IVIM and mDixon-Quant multiparameter imaging in quantitatively assessing PNI in CC. Approach: MRI scans were conducted on 36 patients with CC to explore the correlation and diagnostic efficacy between MRI quantitative parameters and PNI in CC. Results: The combined assessment of IVIM and mDixon-Quant quantitative parameters demonstrated a correlation with PNI in CC ,could determine the status of CC PNI. Impact: The quantitative parameters derived from IVIM and mDixon-Quant MRI are significantly associated with PNI in cervical carcinoma. These parameters hold promising clinical application prospects for evaluating neural invasion in cervical carcinoma.