Simplified LI-RADS Table for Hepatocellular Carcinoma Diagnosis on Extracellular-Contrast Enhanced MRI: AFP as an Additional Major Feature

Motivation: The MRI LI-RADS v2018 table is complex and has insufficient sensitivity. Goal(s): To evaluate the diagnostic performance of the simplified LI-RADS table for HCC on ECA-MRI, and to determine the value of AFP level as an additional major feature. Approach: We developed and compared the per-lesion sensitivity for HCC defined by LI-RADS v2018, simplified LI-RADS table, and both of them combined with AFP ≥ 200 ng/mL. Results: Compared with LR-5 v2018, the simplified LI-RADS table provided higher sensitivity and comparable specificity for HCC. AFP ≥ 200 ng/mL may be a suitable additional major feature for further improving LR-5 v2018 and sLR-5 classification. Impact: Our simplified LI-RADS table may be more convenient and clinically helpful, and the AFP ≥ 200 ng/mL may be a suitable additional major feature for accurate LR-5 and sLR-5 classification.

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Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/4142
Primary Topic
Radiomics and Machine Learning in Medical Imaging
Type
article
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article

Simplified LI-RADS Table for Hepatocellular Carcinoma Diagnosis on Extracellular-Contrast Enhanced MRI: AFP as an Additional Major Feature

Yufeng Wang, Hang Jiang, Han Yu, Tianhui Zhang et al.
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Radiomics and Machine Learning in Medical Imaging
article

Simplified LI-RADS Table for Hepatocellular Carcinoma Diagnosis on Extracellular-Contrast Enhanced MRI: AFP as an Additional Major Feature

Yufeng Wang, Hang Jiang, Han Yu, Tianhui Zhang, Jin Wang, Yang Yang, Yao Zhang, Linqi Zhang, Jingbiao Chen, Lichun Chen, Jinhui Zhou, Xi Zhong, Yikai Xu, Jing Zhang
article en

Abstract

Motivation: The MRI LI-RADS v2018 table is complex and has insufficient sensitivity. Goal(s): To evaluate the diagnostic performance of the simplified LI-RADS table for HCC on ECA-MRI, and to determine the value of AFP level as an additional major feature. Approach: We developed and compared the per-lesion sensitivity for HCC defined by LI-RADS v2018, simplified LI-RADS table, and both of them combined with AFP ≥ 200 ng/mL. Results: Compared with LR-5 v2018, the simplified LI-RADS table provided higher sensitivity and comparable specificity for HCC. AFP ≥ 200 ng/mL may be a suitable additional major feature for further improving LR-5 v2018 and sLR-5 classification. Impact: Our simplified LI-RADS table may be more convenient and clinically helpful, and the AFP ≥ 200 ng/mL may be a suitable additional major feature for accurate LR-5 and sLR-5 classification.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
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Openalex Percentile: Top 64%
Radiomics and Machine Learning in Medical Imaging
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Simplified LI-RADS Table for Hepatocellular Carcinoma Diagnosis on Extracellular-Contrast Enhanced MRI: AFP as an Additional Major Feature — Yufeng Wang, Hang Jiang, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2024) | TGRS Research Map | TGRS