ZOOM and enhance: ZOnally magnified Oblique Multi-slice for cardiac DTI with ultra-strong gradients

Motivation: Cardiac diffusion tensor imaging (cDTI) with echo-planar imaging (EPI) requires long readouts to avoid aliasing artefacts if 2D-selective rf-pulses are not available. These prolong the echo time (TE) and increasing sensitivity to off-resonance artefacts. Goal(s): The reduction of the excited and refocused field of view in the phase direction to reduce TE and sensitivity to image artefacts in cDTI. Approach: We combine ZOnally-magnified Oblique Multi-slice (ZOOM) EPI (i.e. tilting the slice orientation of the refocussing rf-pulse) with ultra-strong gradients. Results: We were able to reduce TE (from ~70 ms to 59 ms) in cDTI considerably by reducing the FoV and using strong gradients. Impact: We reduced the echo time in cDTI with ultra-strong gradients which will allow us to use more advanced diffusion acquisitions (higher b-values and/or different gradient waveforms) in the heart in vivo.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/1269
Citations
4
Primary Topic
Advancements in Photolithography Techniques
Type
article
Field-Weighted Citation Impact
0.83
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article

ZOOM and enhance: ZOnally magnified Oblique Multi-slice for cardiac DTI with ultra-strong gradients

Jürgen E. Schneider, Derek Kenton Jones, Maryam Afzali, John R. Evans et al.
4 citations
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Advancements in Photolithography Techniques
0.83
article

ZOOM and enhance: ZOnally magnified Oblique Multi-slice for cardiac DTI with ultra-strong gradients

Jürgen E. Schneider, Derek Kenton Jones, Maryam Afzali, John R. Evans, Sam Coveney, Erica Dall’Armellina, Filip Szczepankiewicz, Irvin Teh, André Döring, Fabrizio Fasano, Lars Mueller
article en
4 citations

Abstract

Motivation: Cardiac diffusion tensor imaging (cDTI) with echo-planar imaging (EPI) requires long readouts to avoid aliasing artefacts if 2D-selective rf-pulses are not available. These prolong the echo time (TE) and increasing sensitivity to off-resonance artefacts. Goal(s): The reduction of the excited and refocused field of view in the phase direction to reduce TE and sensitivity to image artefacts in cDTI. Approach: We combine ZOnally-magnified Oblique Multi-slice (ZOOM) EPI (i.e. tilting the slice orientation of the refocussing rf-pulse) with ultra-strong gradients. Results: We were able to reduce TE (from ~70 ms to 59 ms) in cDTI considerably by reducing the FoV and using strong gradients. Impact: We reduced the echo time in cDTI with ultra-strong gradients which will allow us to use more advanced diffusion acquisitions (higher b-values and/or different gradient waveforms) in the heart in vivo.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 26%
Advancements in Photolithography Techniques
0.83
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ZOOM and enhance: ZOnally magnified Oblique Multi-slice for cardiac DTI with ultra-strong gradients — Jürgen E. Schneider, Derek Kenton Jones, et al. · Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition (2024) | TGRS Research Map | TGRS