The diagnostic value of myocardial diffusion combined with T1mapping、ECV in the evaluation of myocardial salvage in acute myocardial infarction

Motivation: Cardiac MRI with diffusion-weighted imaging (DWI) non-invasively characterizes myocardial infarction, potentially identifying salvageable 'gray zone' areas without contrast agents. Goal(s): This study aimed to evaluate the diagnostic value of DWI combined with T1 mapping, ECV, and LGE in assessing viable myocardium in acute MI patients. Approach: By comparing ADC values across infarcted, peri-infarct, and healthy myocardium, significant ADC discrepancies highlighted the viability of the 'gray zone.'Results: These findings could influence treatment strategies to recover endangered myocardium, enhancing clinical outcomes in acute myocardial infarction scenarios. Impact: Investigating the 'gray zone' through CMR DWI sequences and ADC value changes, this study advances our understanding of myocardial viability in acute MI, potentially guiding interventions to salvage myocardium and improve patient outcomes in acute ischemic events.