The prediction value of CMR first-pass perfusion parameters for left ventricular reverse remodeling in dilated cardiomyopathy

Motivation: CMR first-pass-perfusion imaging (FPI) had revealed coronary microvascular dysfunction (CMD) in dilated cardiomyopathy (DCM). However, it’s unknown if FPI could predict left ventricular reverse remodeling (LVRR) in DCM. Goal(s): Investigating the value of FPI parameters for predicting LVRR. Approach: 94 DCM patients and 35 healthy controls were enrolled. FPI as well as the left ventricular structure, function and late gadolinium enhancement (LGE) parameters were analyzed. Results: FPI showed more serious CMD in non-LVRR than LVRR. Timemax of FPI as well as left ventricular remodeling index and LGE extent were independent predictors. Impact: This study firstly showed the role of FPI in predicting LVRR in DCM.