Assessment of a long label duration in multi-delay pseudo-continuous arterial spin labelling scheme

Motivation: Clinical usefulness of multi-delay (MD) as well as long label duration (LD) pseudo-continuous arterial spin labelling (pCASL) have been suggested. However, MD-pCASL scheme including long LD has not been established. Goal(s): Long LD combined MD-pCASL scheme was assessed in terms of quantification. The possibility of scan acceleration was also studied. Approach: MD-pCASL with maximum LD 3 sec for 11 (3min 13sec) and 5 delays (1min 38sec) were assessed, and compared to a scheme with maximum LD 2 sec. Results: Reasonable quantitative values were obtained by both LD 3 sec schemes, while providing higher SNR. Impact: The potential of a MD-ASL scheme with long label duration has been demonstrated in terms of improved SNR, reasonable quantitative parameters, and acceleration of scan time. Advantages of the scheme are especially expected for neurovascular applications.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/2306
Primary Topic
Advanced MRI Techniques and Applications
Type
article
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Assessment of a long label duration in multi-delay pseudo-continuous arterial spin labelling scheme

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Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Advanced MRI Techniques and Applications
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Assessment of a long label duration in multi-delay pseudo-continuous arterial spin labelling scheme

Ryoji Mikayama, Marc Van Cauteren, Shota Ishida, Makoto Obara, Osamu Togao, Tatsuhiro Wada, Masami Yoneyama, Kim van de Ven, Chiaki Tokunaga, Matthias J.P. van Osch, Yuki Ito, Lena Václavů, Hiroshi Hamano, Yu Ueda, Kwon Jihun
article en

Abstract

Motivation: Clinical usefulness of multi-delay (MD) as well as long label duration (LD) pseudo-continuous arterial spin labelling (pCASL) have been suggested. However, MD-pCASL scheme including long LD has not been established. Goal(s): Long LD combined MD-pCASL scheme was assessed in terms of quantification. The possibility of scan acceleration was also studied. Approach: MD-pCASL with maximum LD 3 sec for 11 (3min 13sec) and 5 delays (1min 38sec) were assessed, and compared to a scheme with maximum LD 2 sec. Results: Reasonable quantitative values were obtained by both LD 3 sec schemes, while providing higher SNR. Impact: The potential of a MD-ASL scheme with long label duration has been demonstrated in terms of improved SNR, reasonable quantitative parameters, and acceleration of scan time. Advantages of the scheme are especially expected for neurovascular applications.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 64%
Advanced MRI Techniques and Applications
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