MRI Assessment of Sensitivity to Carbon Ion Irradiation in Rat C6 Glioma

Motivation: What is the specific efficacy of carbon ion radiation in the treatment of brain gliomas?Goal(s): To assess the specific effect of carbon ion irradiation in inhibiting the growth and peritumor infiltration of gliomas. Approach: Establishment of a rat C6 brain glioma model with carbon ion irradiation and assessment of the efficacy response of brain glioma after carbon ion irradiation using MRI multiparametric imagingResults: MRI multiparametric imaging can reflect the inhibitory effect of carbon ion irradiation on the growth and invasion of gliomas. Impact: CIRT for glioma is still in the stage of clinical trials, the number of subjects is limited, and its specific efficacy still needs to be explored. Our study provides an experimental basis for the clinical application of CIRT for gliomas.