Automatic rhythmic pressuring leading to instantly promotes drowsiness at RN12 site.

Motivation: This study is motivated by the increasing interest in non-pharmacological approaches, like RN12-ARP, to improve sleep quality and address sleep-related problems. Goal(s): The specific aim is to investigate RN12-ARP's effects on sleepiness, EEG patterns, and brain activity in individuals with insomnia, exploring its potential as a solution for sleep disturbances. Approach: Seventeen participants undergo RN12-ARP sessions, collecting EEG, sleep diaries, and psychological assessments, analyzed using high-density EEG and MRI. Results: The study shows that RN12-ARP induces immediate sleepiness, supported by EEG-fMRI. Psychological scales have limited effects, but sleep diaries hint at improved sleep, suggesting potential for insomnia treatment, pending further research. Impact: The study might pave the way for non-pharmacological interventions like RN12-ARP to address insomnia, improving the well-being of patients with sleep disturbances. Further investigations into the mechanisms behind quick drowsiness are pending, offering hope for alternative approaches to sleep therapy.