Myelin-sensitive inversion recovery (MySIR) for quantification of myelin in the peripheral nerve

Motivation: Quantification of myelin in peripheral nerves remains challenging. Goal(s): To evaluate new imaging techniques that quantify myelin in the peripheral nerve. Approach: Myelin-sensitive inversion recovery (MySIR) was compared with inhomogeneous magnetization transfer (ihMT) for its ability to reflect myelin value and spatial resolution in the peripheral nerve. Results: Myelin values of MySIR and ihMT were strongly correlated. MySIR had a better ability to visualize nerve fascicles than ihMT. Impact: MySIR could quantify myelin while maintaining high spacial resolution in peripheral nerves.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/1885
Primary Topic
Peripheral Nerve Disorders
Type
article
Field-Weighted Citation Impact
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article

Myelin-sensitive inversion recovery (MySIR) for quantification of myelin in the peripheral nerve

Hirotaka Sato, Hajime Yokota, Keisuke Nitta, Takashi Uno et al.
1 links
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Peripheral Nerve Disorders
article

Myelin-sensitive inversion recovery (MySIR) for quantification of myelin in the peripheral nerve

Hirotaka Sato, Hajime Yokota, Keisuke Nitta, Takashi Uno, Masami Yoneyama, Yoshitada Masuda, Takashi Namiki, Takayuki Sada, Ryuna Kurosawa, Guillaume Gilbert, Koji Matsumoto
article en

Abstract

Motivation: Quantification of myelin in peripheral nerves remains challenging. Goal(s): To evaluate new imaging techniques that quantify myelin in the peripheral nerve. Approach: Myelin-sensitive inversion recovery (MySIR) was compared with inhomogeneous magnetization transfer (ihMT) for its ability to reflect myelin value and spatial resolution in the peripheral nerve. Results: Myelin values of MySIR and ihMT were strongly correlated. MySIR had a better ability to visualize nerve fascicles than ihMT. Impact: MySIR could quantify myelin while maintaining high spacial resolution in peripheral nerves.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 64%
Peripheral Nerve Disorders
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