Physiological and macropathological results in swine model at 123 MHz in experimental setup for investigating thresholds of tissue damage

Motivation: Radiofrequency used during MRI exams heat tissue. The temperature increase is unknown and the thermoregulatory responses still need to be analyzed. Goal(s): To analyse the temperatures within the thresholds. Are any changes seen. Is the biological simulation replicable in living swine. Approach: SAR levels in the 2.mode were planned in the swine as an animal model. Results: The thermoregulatory model (temperature going into a plateau) is only one pattern next to 3 other patterns (linear, parabolic, and sinusoidal). So these will change the calculations of simulations for temperatures in humans receiving MRI exams. Impact: Radiofrequency induced temperature changes in MRI exams need to be reevaluated as new thermoregulatory patterns are observed. Increased internal temperatures are subconsciously discerned causing thermoregulation to avoid tissue damage.

Authors

Publication Details

Journal
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Published
2024-11-26
DOI
https://doi.org/10.58530/2024/3959
Primary Topic
Ultrasound and Hyperthermia Applications
Type
article
Field-Weighted Citation Impact
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article

Physiological and macropathological results in swine model at 123 MHz in experimental setup for investigating thresholds of tissue damage

Chie Hee Cho, Lutz Lüdemann
Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Ultrasound and Hyperthermia Applications
article

Physiological and macropathological results in swine model at 123 MHz in experimental setup for investigating thresholds of tissue damage

Chie Hee Cho, Lutz Lüdemann
article en

Abstract

Motivation: Radiofrequency used during MRI exams heat tissue. The temperature increase is unknown and the thermoregulatory responses still need to be analyzed. Goal(s): To analyse the temperatures within the thresholds. Are any changes seen. Is the biological simulation replicable in living swine. Approach: SAR levels in the 2.mode were planned in the swine as an animal model. Results: The thermoregulatory model (temperature going into a plateau) is only one pattern next to 3 other patterns (linear, parabolic, and sinusoidal). So these will change the calculations of simulations for temperatures in humans receiving MRI exams. Impact: Radiofrequency induced temperature changes in MRI exams need to be reevaluated as new thermoregulatory patterns are observed. Increased internal temperatures are subconsciously discerned causing thermoregulation to avoid tissue damage.

Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
Openalex Percentile: Top 80%
Ultrasound and Hyperthermia Applications
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