Physiological and macropathological results in swine model at 123 MHz in experimental setup for investigating thresholds of tissue damage
Motivation: Radiofrequency used during MRI exams heat tissue. The temperature increase is unknown and the thermoregulatory responses still need to be analyzed. Goal(s): To analyse the temperatures within the thresholds. Are any changes seen. Is the biological simulation replicable in living swine. Approach: SAR levels in the 2.mode were planned in the swine as an animal model. Results: The thermoregulatory model (temperature going into a plateau) is only one pattern next to 3 other patterns (linear, parabolic, and sinusoidal). So these will change the calculations of simulations for temperatures in humans receiving MRI exams. Impact: Radiofrequency induced temperature changes in MRI exams need to be reevaluated as new thermoregulatory patterns are observed. Increased internal temperatures are subconsciously discerned causing thermoregulation to avoid tissue damage.
Authors
- Chie Hee Cho (ORCID: https://orcid.org/0000-0001-6717-2155)
- Lutz Lüdemann
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/3959
- Primary Topic
- Ultrasound and Hyperthermia Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00