Multiparametric magnetic resonance imaging findings of the pancreas: Comparison in patients with type 1 and type 2 diabetes

Motivation: The diabetes-related pancreatic changes on MRI remain to be fully elucidated. Goal(s): Our goal was to determine characteristic imaging findings of the pancreas on MRI in patients with type 1 diabetes (T1D) and type 2 diabetes (T2D). Approach: Seven T1D patients and fifty-four T2D patients were imaged using multiparametric pancreatic MRI including T1 map, PDFF map, ADC map and cine-dynamic MRCP, and were compared to control patients. Results: T1D patients had reduced pancreatic size, increased pancreatic T1 and ADC values, and decreased pancreatic juice flow on cine-dynamic MRCP. T2D patients had increased pancreatic PDFF. Impact: Multiparametric MRI provided valuable information on pancreatic changes in both T1 and T2 diabetes and may be useful for assessing pancreatic endocrine and exocrine insufficiency and pancreatic pathological changes in patients with diabetes.