ISMRM - Open Science Initiative for Perfusion Imaging (OSIPI): The multi-delay Arterial Spin Labeling Challenge

Motivation: The OSIPI ASL Challenge is a community initiative motivated by open science principles that aim to establish good practices in ASL image analysis and Cerebral Blood Flow (CBF) quantification. Goal(s): The second ASL challenge's main goal is to provide a thorough comparison of existing post-processing pipelines focusing on Multi-PLD methodology. Approach: The second roadmap will provide different datasets; a population dataset which will bring real variability to the challenge and synthetic data which allows straightforward ground truth comparison. Results: The second edition of the ASL Challenge will contribute to gaining new insights into the potential sources of variability within the multi-PLD analysis pipeline. Impact: Through the second edition of the ASL Challenge, we seek to enhance our understanding of multi-PLD analysis in the ASL community. Its success could establish a consensus on the processing of multi-PLD ASL data, positively influencing clinical and scientific practices.