Automatically Quantitative Intra-tumoral susceptibility Signal and R2 star in discriminating subtype of ovarian cancer

Motivation: It is important to quantitatively analyze the subtype of epithelial ovarian cancer using oxygen content, neovascularization, intra-tumoral hemorrhage. Goal(s): To investigate the R2* value of ESWAN and quantitative ITSS obtained automatically in discriminating subtype of epithelial ovarian cancer. Approach: R2* value of ESWAN sequence and ITSS ratio of ovarian cancer lesion were measured, and the value of R2* and ITSS in discriminating subtype of EOC was analyzed. Results: The area ITSS ratio and volume ITSS ratio of type II ovarian cancer were significantly higher than those of type I EOC. There was no significant difference between type I and type II EOC. Impact: The area ITSS ratio and volume ITSS ratio have certain value in discriminating type I from type II EOC. The value of R2* value in the differentiation of subtype of epithelial ovarian cancer need to be further explored.