MULTI-PHASE SPATIAL RECONSTRUCTION METHOD FOR ACCELERATED DYNAMIC CONTRAST-ENHANCED MRI

Motivation: Dynamic contrast-enhanced (DCE) MRI requires both high spatial and high temporal resolution for accurate quantification and delineation. In practice, temporal resolution is often traded for spatial resolution and volume coverage. Goal(s): To develop a reconstruction method that offers both high spatial and temporal resolution. Approach: We describe a two-stage reconstruction technique that consistently produces high-temporal, high-spatial resolution estimates of the ground truth data and is more accurate than current state-of-the-art methods. Results: The proposed method achieves high quality reconstruction with as few as one acquired spoke per frame when radial sampling is used. Impact: The theoretical and practical success of the spatial subspace method over temporal subspace methods encourages further research on the topic. Furthermore, reconstruction at 1 spoke per frame enables larger imaging volumes, thus more capable imaging tools.