Prognostic Value of Left Atrial Strain Analysis by using CMR-FT for patients with Acute Myocarditis

Motivation: The prognostic significance of left atrial strain (LA) in acute myocarditis (AM) remains unknown. Goal(s): This study aimed to conduct a quantitative evaluation of the LA function in AM patients and explore whether LA strain parameters can predict the outcomes of AM patients. Approach: LA strain was assessed by using cardiovascular magnetic resonance feature tracking (CMR-FT) in this study. Results: LA strain parameters were significantly impaired in AM patients with major adverse cardiovascular events (MACEs) and reservoir LA longitudinal strain was found to be an independent predictor of MACEs, with a hazard ratio per 1% increase of 0.954 (P<0.05). Impact: LA reservoir strain may serve as a useful tool to predict the adverse prognosis of AM and have the potential to guide the distant therapy of patients with acute myocarditis.