Myocardial Strain Disparities in Genetic and Secondary Dilated Cardiomyopathy: Insights from Cardiac Magnetic Resonance Imaging

Motivation: Dilated Cardiomyopathy (DCM) poses a significant clinical challenge due to its high mortality and limited cognitive understanding. Our motivation is rooted in enhancing diagnostic precision, unraveling novel insights into DCM pathology, and paving the way for targeted therapeutic interventions. Goal(s): This study aims to unravel the intricate myocardial strain patterns in DCM patients through cardiac MRI techniques. Approach: In this study, feature tracking method were used to evaluate myocardial strain. Results: There is no significant difference in global left ventricular strain, variations emerge in segmental myocardial strain between genetic and secondary DCM patients. The myocardial strain rate exhibits disparities both globally and segmentally. Impact: This study unveils nuanced myocardial strain disparities in DCM, which could be utilized to illuminate diagnostic precision. The insights catalyze targeted therapeutic strategies, potentially revolutionizing care for DCM patients.