Predictive value of left atrial and left ventricular strain for sudden cardiac death risk in hypertrophic cardiomyopathy by feature-tracking CMR

Motivation: The risk stratification for implantable cardioverter-defibrillators (ICD) placement in high-risk patients with hypertrophic cardiomyopathy (HCM) has challenges. Goal(s): The aim of this study is to investigate the connection between left atrial and left ventricular strain and sudden cardiac death (SCD) risk stratification by feature-tracking CMR. Approach: All patients were satisfied by the 2020 AHA/ACC HCM Risk-SCD model with feature-tracking CMR for assessing left atrial and left ventricular strain. Results: Results demonstrated that both left atrial and left ventricular strain show obvious attenuation in high-risk group than low-risk group. LVGRS+LARS combined model exhibited a superior diagnostic value for identifying high-risk SCD. Impact: The LVGRS+LARS combined model could provide additional predictive value for improving SCD risk stratification in clinical practice, which may provide vital insights into the judicious clinical utilization of ICD to reduce SCD in HCM.