Prediction of varices risk in patients with liver cirrhosis based on the 4D Flow MRI technique

Motivation: The gold standard for clinical diagnosing varices is invasive gastroscopy. However, there is a need for a non-invasive method to accurately assess the risk of varices in cirrhotic patients. Goal(s): Exploring the potential of 4D Flow MRI flow quantification technique in predicting the risk of varices in patients with cirrhosis. Approach: Fifty-three patients with liver cirrhosis and twenty-seven healthy volunteers underwent clinically relevant examinations and 4D Flow MRI imaging. The hemodynamic parameters obtained from the imaging data were analyzed. Results: The combined index of main portal vein and splenic vein hemoflow effectively predicted the occurrence of varices in cirrhotic patients. Impact: The use of 4D Flow MRI for predicting varices risk in liver cirrhosis patients offers a non-invasive alternative to invasive gastroscopy, improving patient comfort and reducing risks. Additionally, this study advanced non-invasive diagnostics and personalized treatment strategies.