Deep learning based reconstruction 3D ZTE-MRI for calcium deposit using computed tomography as reference

Motivation: Screening opportunity might increase detection of calcium presence in cardiac tissues. Calcium deposit in cardiac tissues especially vessels alter flow hemodynamics. A non-invasive zero echo time magnetic resonance imaging (ZTE-MRI) may offer additional information when patients receive routine cardiac magnetic resonance imaging (CMR). Goal(s): To propose a three-minute, high-resolution, high-SNR free-breathing ZTE-MRI in detection of coronary artery calcification. Approach: To subjectively and objectively evaluation of ZTE-MRI respectively using conventional and deep learning reconstruction using CT as reference. Results: DLR ZTE-MRI had superior image quality to noDLR ZTE-MRI and showed fair to good performance on calcium deposit by visual observation. Impact: DLR ZTE-MRI with the featurs of fee-radiation, silence, and comfort (free-breathing) during scan can provide extra information – calcium deposite, for whoever, especially a CKD patient, plans to receive a physical examination especially CMR examinaition.