Association Between Epicardial Adipose Tissue volume and Microvascular Obstruction in Patients with STEMI

Motivation: Microvascular obstruction (MVO) after primary percutaneous coronary intervention (pPCI) is identifed as an independent risk factor for poor prognosis in patients with acute myocardial infarction (AMI). However, the clinical implications of Epicardial adipose tissue (EAT) in microvascular obstruction formation in patients with ST-segment elevation myocardial infarction (STEMI) remain unclear. Goal(s): This study aimed to evaluate the correlation between EAT and MVO volume detected by CMR in STEMI patients. Approach: Cardiac magnetic resonance (CMR) has emerged as the gold standard technique to detect the extent of MVO and evaluate EAT volume. Results: Left atrioventricular EAT mass index is an independent predictor of MVO. Impact: Measurement of EAT using CMR could be used for risk stratification and may be a promising target in developing new therapies to reduce myocardial reperfusion injury in patients with STEMI.