The value of Synthetic Magnetic Resonance Imaging in differentiating Muscular Invasion in Bladder Cancer

Motivation: The evaluation of muscular invasion in bladder cancer is essential for determining the optimal surgical approach for patients1. The application of Synthetic magnetic resonance imaging (MAGic resonance imaging, MAGiC) in assessing muscular invasion has not been reported previously2. Goal(s): To assess the value of MAGiC in diagnosing muscular invasion in bladder cancer. Approach: This study evaluated the differences of T1/T2/ADC and VI-RADS between non-muscle invasive and muscle invasive lesions and the differentiation performance of the indices. Results: Improved diagnosis performance was obtained with combined T2 relaxometry and VI-RADS in compared with each single index. Impact: The findings of this study demonstrate that quantitative MRI parameters enhance the precision and objectivity of assessing muscular invasion in bladder cancer, exhibiting minimal dependence on the clinical experience of diagnostic physician, thus holding promise for their wide-ranging application.