Feasibility of T2 mapping for the detection of myocardial injury in hypertrophic cardiomyopathy

Motivation: The relationship between T2 value and myocardial injury has not been well demonstrated. Goal(s): To explore the association between T2 value and myocardial injury in HCM patients. Approach: 50 patients with HCM were prospectively recruited. Hs-cTnI was obtained as a marker of myocardial injury (>0.016ng/mL). ConSept T2 were measured from the maximal value of 16 segments and the middle septum. Results: The hs-cTnI elevated group had higher T2 global, ConSept T2, T2 max(P<0.05) than the normal hs-cTnI group. The ConSept T2 value were moderately correlated with hs-cTnI(r=0.52, P<0.001). In logistic regression analysis, ConSept T2 value was significantly associated with elevated hs-cTnI(P<0.01)Impact: This study provided in-vivo evidence by CMR for the ongoing myocardial injury in HCM.