Characterisation of brain T2* Values across the neonatal period at 7 Telsa
Motivation: Brain T2* values can provide information about tissue specific maturation, and can also provide knowledge important for optimising echo times for fMRI acquisition. Goal(s): To characterise tissue specific T2* values in the neonatal brain at 7T. Approach: Whole brain T2* maps from 14 neonates were generated using a 3D multi-echo acquisition. Results: Median T2* values were: cortical grey matter: 58 ms, deep grey matter: 70 ms and white matter: 86 ms. Values differ markedly from those described in adults and measured at standard field strengths. Impact: We describe tissue-specific T2* values in the neonatal brain at 7T, which may provide new information about brain development in health and disease, and provide a basis for optimising fMRI sequences for neonates at 7T.
Authors
- Shaihan Malik (ORCID: https://orcid.org/0000-0001-8925-9032)
- Maria Deprez (ORCID: https://orcid.org/0000-0002-2799-6077)
- Alena Uus (ORCID: https://orcid.org/0000-0001-5796-2145)
- Anthony N. Price (ORCID: https://orcid.org/0000-0002-6907-7554)
- Tomoki Arichi (ORCID: https://orcid.org/0000-0002-3550-1644)
- Philippa Bridgen (ORCID: https://orcid.org/0009-0008-8051-8139)
- Jucha Willers Moore (ORCID: https://orcid.org/0000-0003-0916-918X)
- Joseph V. Hajnal (ORCID: https://orcid.org/0000-0002-2690-5495)
- Elisabeth Pickles (ORCID: https://orcid.org/0000-0003-4974-4943)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/4983
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00