Spatiotemporally Encoded Single-Sided MRI with a Numerical Point-Spread Function Reconstruction

Motivation: Motivation: Single-sided MRI scanners offer excellent interventional access but require novel approaches to image acquisition. Goal(s): To generate distortion-free spatiotemporally encoded images with a single-sided low-field MRI scanner and validate the acquisitions in vivo. Approach: Spatiotemporally encoded images were collected in phantom and volunteer and reconstructed using a numerical PSF-based reconstruction. Results: Images of male and female subjects showed anatomic structures. Reconstruction with a numerical modeled PSF increased visibility of these structures and improved signal across the field of view in both phantom and human images relative to using a sinc-based PSF. Impact: This methodology can be used for translation of an xSPEN encoded sequence into clinical practice and aid other researchers facing similar reconstruction challenges.