T2-Weighted MR Neurography and Muscle Evaluation Using GRAPPATINI T2 Mapping

Motivation: To evaluate the feasibility and reliability of an accelerated T2 mapping technique (GRAPPATINI) for MR neurography and muscle evaluation. Goal(s): The study aims to qualitatively and quantitatively evaluate GRAPPATINI for MR neurography in patients with foot drop. Approach: To compare the image quality from GRAPPATINI T2-weighted images against conventional T2-weighted images, and to compare T2 values between abnormal and normal muscles. Results: No significant qualitative differences were observed between GRAPPATINI and conventional images diagnostically; there was complete agreement in assessment of nerve signal hyperintensity and size, and muscle edema. Significant differences in GRAPPATINI T2 values were observed between abnormal and normal muscles. Impact: In one acquisition, GRAPPATINI can simultaneously provide clinically equivalent qualitative information and quantitative T2 maps for MR neurography evaluation of foot drop.