A GPU-Accelerated Software Toolbox for Simulation and Analysis of Diffusion MRI in Microstructures with a Graphical User Interface

Motivation: Simulation and analysis of diffusion MRI (dMRI) in microstructures requires specialized expertise that limits its wide usage. Goal(s): To provide an easy-to-use dMRI software package to enable end users to simulate and analyze diffusion in complex media. Approach: MATI is written using object-oriented programming in two versions (MATLAB and Python) and can be used via a GUI or scripts. It can handle typical diffusion pulse sequences and various microstructures for data fitting, and arbitrary digitalized microstructures for simulating dMRI with GPU acceleration. Results: A GPU-accelerated dMRI simulation and data fitting toolbox with a GUI has been developed for public use. Impact: MATI, a GPU-accelerated toolbox for simulating and analyzing dMRI signals in various microstructures with a graphical user interface (GUI), has been developed. This easy-to-use package enables non-expert and expert users to simulate and analyze diffusion MRI signals in complex media.