Cardiac Characteristics in Pulmonary Hypertension Patients with Varying Cardiac Index: A Preliminary Study

Motivation: The prognosis of advanced pulmonary hypertension (PH) is poor, and incorrect treatment methods may accelerate this process. Goal(s): To comprehensively investigate the characteristics of PH by employing various imaging sequences, including 4D Flow, cardiac cine, T1/T2mapping. Approach: CMR imaging was performed on different cardiac index (CI) of PH patients and healthy volunteers to calculate various parameters of the heart and pulmonary arteries. Wilcoxon rank test was used to evaluate inter group differences. Results: A multi-sequence MRI approach effectively detects and characterizes abnormal heart and pulmonary artery features in PH of different CI, offering insights for early diagnosis and clinical management. Impact: The research has provided initial insights into the cardiac characteristics of high-CI and low-CI PH patients using magnetic resonance imaging (MRI) technology. It offers new data and perspectives to better understand the physiological and pathological changes in these patients.