Association between cerebral blood flow and cerebral small vessel disease: a comparison between ASL and phase-contrast MRI
Motivation: Chronic hypoperfusion is a central mechanism of cerebral small vessel disease (CSVD), but studies using different methods have shown different results. Goal(s): To compare the associations between CSVD and CBF measured by phase-contrast MRI and ASL in the same cohort. Approach: 69 subjects were totally recruited in the study. WMH, FW, and tFA were used to reflect the disease severity. The associations between CSVD and CBF measured by two methods were investigated. Results: Compared to CBFPC, CBFASL showed a negative association with FW and a positive association with tFA. The ratio of CBFASL to CBFPC was also correlated with FW and tFA. Impact: Future studies need to consider the differences between CBF measured by ASL and phase-contrast MRI and choose a more appropriate method according to the research purpose.
Authors
- Kaicheng Li (ORCID: https://orcid.org/0000-0001-5500-7523)
- Peiyu Huang (ORCID: https://orcid.org/0000-0003-4226-9369)
- Lei Cui (ORCID: https://orcid.org/0000-0002-7611-1431)
- Li Zhao (ORCID: https://orcid.org/0000-0002-1318-3833)
- Shan Xu (ORCID: https://orcid.org/0000-0002-0864-8851)
- Linyun Xie
- Jixuan Li (ORCID: https://orcid.org/0000-0001-8084-0314)
- Minming Zhang (ORCID: https://orcid.org/0000-0003-0145-7558)
- Yao Yu Zhang (ORCID: https://orcid.org/0009-0009-6922-5818)
- Lingyun Liu (ORCID: https://orcid.org/0000-0002-0421-2006)
- Lin Miao (ORCID: https://orcid.org/0000-0003-0248-2544)
- Xiao Luo
- Ruiting Zhang (ORCID: https://orcid.org/0000-0002-8464-8474)
- Shuyue Wang (ORCID: https://orcid.org/0000-0002-5861-5986)
- Jiaxin Zheng (ORCID: https://orcid.org/0000-0002-8796-0551)
- Hui Hong (ORCID: https://orcid.org/0000-0003-2084-203X)
- Qingze Zeng (ORCID: https://orcid.org/0009-0001-5894-4405)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/2062
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00