Age and sex-matched intracardiac force analysis for repaired tetralogy of fallot patients using 4D flow MRI

Motivation: Cardiac force analysis shows promise for non-invasive treatment and diagnosis for patients with heart disease. Goal(s): Assessing intracardiac forces as a metric of diagnostics in repaired tetralogy of fallot patients which require lifelong monitoring. Approach: Intracardiac forces were analyzed using segment in twenty rTOF patients and 20 control patients. These were compared in age and sex-matched groups. Results: Age and sex-matched analysis showed significant differences in intracardiac forces for control and patient groups. Results also indicated that men and women may be affected differently by rTOF, as there were significant differences between the gender groups with rTOF. Impact: Evaluation of intracardiac forces shows promise as a biomarker for heart disease in rTOF females and males; also demonstrates potential for other diseases, although more investigations must be conducted. This can be used in clinical settings, for non-invasive diagnoses.