Left Ventricular Dyssynchrony in Anterior ST-Elevation Myocardial Infarction

Motivation: Since the septal function is critical to the global LV function and prognosis, we suggest further refining global and segmental septal viability analysis. Goal(s): This study aimed to characterize myocardial strain alterations by CMR-feature tracking for patients with anterior STEMI. Approach: The size of the infarction and the extent of injury, to investigate if any changes in septal function would affect the balance of strain. Results: The infarcted septum swings in a bimodal mode, and myocardial injury reduces the radial strain contractility. A more than 75% transmural degree was the septal strain-contraction reserve cut-off point. Impact: The combination of CMR-LGE and strain puts forward an efficient risk stratification. This technique can help clinicians make accurate decisions, especially for patients with LBBB, avoiding the LV lead placed in the infarcted zone.