Correction of B0-related distortions in diffusion-weighted images of malignant and normal cervical tissue
Motivation: DWI in cervical cancer evaluation suffers from distortions, especially pronounced by intestinal gas, potentially impeding lesion detection/delineation. Goal(s): To evaluate a combined prospective-retrospective distortion reduction approach, based on distortion correction of female pelvic DWI acquired with reduced-FOV. Approach: Two correction methods, RPG and Topup, were applied on images from cervical cancer patients and volunteers. Distortion correction performance was evaluated by the concordance between tumour/cervix borders in images before and after correction. Results: Topup outperformed RPG, with statistically significant but modest improvements of initially small distortions resulting from the reduced-FOV acquisition. Occasional correction failures and limitations in the proton density correction warrant alternative approaches. Impact: Topup distortion correction, commonly used for brain studies, shows statistically significant but modest improvements in female pelvic reduced-FOV DWI. Despite indications of clinical utility, limited improvements and occasional correction failures suggest alternative approaches and prospective distortion reduction as potential strategies.
Authors
- Joshua Kuperman (ORCID: https://orcid.org/0000-0002-7890-4785)
- Rebecca Rakow‐Penner (ORCID: https://orcid.org/0000-0002-2566-1978)
- Katarzyna Kozar (ORCID: https://orcid.org/0000-0002-2397-2975)
- Elin Lundström (ORCID: https://orcid.org/0000-0003-2955-4958)
- Björg Jónsdóttir (ORCID: https://orcid.org/0000-0001-8962-4351)
- Stéphane Loubrie (ORCID: https://orcid.org/0009-0009-0526-2281)
- Ana Rodríguez-Soto (ORCID: https://orcid.org/0000-0002-1553-5177)
- Stephan Jordan
- Marianne S. Hom (ORCID: https://orcid.org/0000-0003-2551-9231)
- Alexandra Schlein (ORCID: https://orcid.org/0000-0002-3821-5723)
- Tyler M. Seibert (ORCID: https://orcid.org/0000-0002-4089-7399)
- Elisabeth Hedlund
- Michael G. Hahn (ORCID: https://orcid.org/0000-0003-2136-5191)
- Anthoula Koliadi
- Anders M. Dale (ORCID: https://orcid.org/0000-0002-6126-2966)
- Christopher C. Conlin (ORCID: https://orcid.org/0000-0003-4509-8702)
- Sheida Ebrahimi
- Per Liss (ORCID: https://orcid.org/0000-0003-4379-0906)
- Shira Varon
- Alexandra H. Besser
- Cheryl Saenz
- Michael McHale (ORCID: https://orcid.org/0000-0002-6471-362X)
Publication Details
- Journal
- Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition
- Published
- 2024-11-26
- DOI
- https://doi.org/10.58530/2024/2581
- Primary Topic
- Radiomics and Machine Learning in Medical Imaging
- Type
- article
- Field-Weighted Citation Impact
- 0.00