Diffusion-weighted imaging of the sellar region: A comparison study of TGSE-BLADE and RESOLVE sequences

Motivation: We aim to investigate the potential of TGSE-BLADE diffusion-weighted imaging(DWI) in mitigating image artifacts and distortions within the sellar region. Goal(s): Our study involves a comparative analysis of image quality between TGSE-BLADE diffusion-weighted imaging (DWI) and RESOLVE-DWI within the sellar region. Approach: We compared qualitative (overall imaging quality, artifacts and distortions) and quantitative (signal-to-noise ratio [SNR] and apparent diffusion coefficient [ADC]) parameters between RESOLVE-DWI and TGSE-BLADE-DWI images. Results: TGSE-BLADE-DWI exhibited higher imaging quality with less artifacts and distortions and a higher SNR than did RESOLVE-DWI (P<0.05). The tissue ADCs did not differ significantly between the groups (P>0.05). Impact: TGSE-BLADE-DWI offers a solution to diffusion imaging distortion. Comparative analysis highlights its superiority in mitigating sellar region distortion, promising enhanced quality in challenging clinical applications.