Correlation between imaging features of lenticulostriate artery and cognitive impairment in patients with cerebral small vessel disease

Motivation: The association between cognitive impairment and lenticulostriate arteries (LSAs) in patients with CSVD remains uncertain. Goal(s): This study aims to investigate the relationship between the imaging characteristics of lenticulostriate arteries (LSAs) and cognitive function in patients with sporadic CSVD. Approach: Forty-seven CSVD patients and 28 healthy people were prospectively recruited. According to the MoCA score and years of education, they were divided into the Non-VCI group and the VCI group . Results: The decrease in the number of LSA was an independent risk factor for VCI in CSVD patients . The number and total length of LSA were significantly correlated with MMSE and MoCA score. Impact: LSAs is associated with overall cognitive dysfunction in CSVD patients, and the number of LSAS is an independent risk factor for VCI in CSVD patients.